Changes in pain and MRI-based synovitis in knee osteoarthritis following intraarticular glucocorticoids and exercise: a randomised controlled trial



The aim of this randomized controlled study is to investigate the changes in MRI-based estimates of synovitis following an exercise program preceded by an intra-articular injection with either glucocorticoid or isotonic saline (placebo). We will furthermore investigate if any of the changes in the patient reported outcome measures are paralleled by changes in the MRI-assessments of synovitis.


Robert GC Riis, Marius Henriksen, Louise Klokker, Cecilie Bartholdy, Karen Ellegaard, Elisabeth Bandak, Henning Bliddal, Mikael Boesen