Long-term incidence of vitrectomy and associated risk factors in young Danish patients with Type 1 diabetes: the Danish Cohort of Paediatric Diabetes 1987
Broe, R., Rasmussen, M. L., Frydkjaer-Olsen, U., Olsen, B. S., Mortensen, H. B., Peto, T. & Grauslund, J., apr. 2015, I: Diabetic Medicine. 32, 4, s. 542-545 4 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
AIMS: To examine the long-term incidence of vitrectomy in young people with Type 1 diabetes.
METHODS: We prospectively studied 324 people with Type 1 diabetes who participated in baseline examinations in 1995. Surgical history was obtained from the Danish National Patient Registry in April 2012.
RESULTS: During the 17-year study period, 39 people (12.0%) underwent vitrectomy at least once. The mean age and diabetes duration at first vitrectomy were 29.8 and 22.9 years, respectively, and 64.1% of the participants were men. In multivariable Cox regression analysis, baseline age (hazard ratio 0.81 per 1 year increase), BMI (hazard ratio 1.21 per 1 kg/m(2) increase), HbA1c (hazard ratio 1.72 per 1% increase) and diabetic retinopathy (hazard ratio 2.85 and 6.07 for mild and moderate/severe diabetic retinopathy vs none, respectively) were independent predictors of vitrectomy (P < 0.05 for all variables).
CONCLUSIONS: Vitrectomy is a relatively common procedure in young people with Type 1 diabetes, with poor glycaemic control being the strongest modifiable risk factor.
Originalsprog | Engelsk |
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Tidsskrift | Diabetic Medicine |
Vol/bind | 32 |
Udgave nummer | 4 |
Sider (fra-til) | 542-545 |
Antal sider | 4 |
ISSN | 0742-3071 |
DOI | |
Status | Udgivet - apr. 2015 |