Atopi hos børn og unge i København
Ulrik, C. S., von Linstow, M. L. & Backer, V., 10 dec. 2001, I: Ugeskrift for Laeger. 163, 50, s. 7070-3 4 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Ulrik, C. S., von Linstow, M. L. & Backer, V., 10 dec. 2001, I: Ugeskrift for Laeger. 163, 50, s. 7070-3 4 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Hansen, T. V., aug. 2001, I: Peptides. 22, 8, s. 1201-11 11 s.
Publikation: Bidrag til tidsskrift › Review › peer review
Andersen, C. & Adamsen, L., jul. 2001, I: Journal of Advanced Nursing. 35, 2, s. 257-67 11 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Harboe, Z. B., Paerregaard, A., Hansen, B. F. & Hesselfeldt, P., feb. 2001, I: Journal of Pediatric Gastroenterology and Nutrition. 32, 2, s. 224-5 2 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Langer, S. W., Sehested, M. & Buhl Jensen, P., 2001, I: Annals of Oncology. 12, 3, s. 405-410 6 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Anhoej, C., Backer, V. & Nolte, H., jun. 2001, I: Allergy. 56, 6, s. 548-52 5 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Kammersgaard, L. P., Jørgensen, H. S., Reith, J., Nakayama, H., Houth, J. G., Weber, U. J., Pedersen, P. M. & Olsen, T. S. 2001 I : Journal of Stroke & Cerebrovascular Diseases. 10, 5, s. 217-221 5 s.
Publikation: Forskning - peer review › Tidsskriftartikel
Originalsprog | Engelsk |
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Tidsskrift | Journal of Stroke & Cerebrovascular Diseases |
Udgivelsesdato | 2001 |
Vol/bind | 10 |
Tidsskriftsnummer | 5 |
Sider | 217-221 |
Antal sider | 5 |
ISSN | 1052-3057 |
DOI | |
Status | Udgivet |
Sørensen, M., Jensen, B. R., Poulsen, H. E., Deng, X., Tygstrup, N., Dalhoff, K. & Loft, S., jun. 2001, I: Food and Chemical Toxicology. 39, 6, s. 533-40 8 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
The apparent anticarcinogenic effect of cruciferous vegetables found in numerous epidemiological and experimental studies has been associated with their influence on phase I and phase II metabolising enzymes as well as on the antioxidant status. In the present study we investigated the effect of administration of a Brussels sprouts extract on the expression at the mRNA level and/or catalytic activity in rat liver of three phase I enzymes [cytochrome P450-1A2 (CYP1A2),-2B1/2 (CYP2B1/2) and-2E1 (CYP2E1)] and two phase II enzyme [NADPH:quinone reductase (QR) and glutathione S-transferase pi 7 (GSTpi)], all previously suggested to be induced by vegetables. We also examined the activity and/or expression of several important antioxidant enzymes: glutathione peroxidase (GPx), catalase and gamma-glutamyl-cysteine synthetase (GCS) and the activity of the repair enzyme 8-oxoguanine DNA glycosylase (OGG1). QR, GPx and catalase activity was also assessed in the kidneys. In order to examine a possible effect of the Brussels sprouts related to oxidative stress, we measured oxidative DNA damage in terms of 7-hydro-8-oxo-2'-deoxyguanosine (8-oxodG) and lipid peroxidation in terms of malondialdehyde (MDA) formation in the liver. Oral administration of an aqueous Brussels sprouts extract for 4 days was found to induce the expression of GST 1.3-fold (P < 0.05) and the activity of QR 2.6-fold in rat liver (P < 0.05). No significant differences were seen in the expression of the phase I enzymes. No differences in antioxidant enzyme activity/expression or OGG1 activity were observed. In a second experiment, administration of the Brussels sprouts extract for 3 or 7 days was found to increase the level of 8-oxodG in rat liver from 0.75 to 0.97 per 10(5) dG and from 0.81 to 0.97 per 10(5) dG, respectively (P < 0.05). No effects on MDA levels were found. The present results support the data obtained in several studies that consumption of cruciferous vegetables is capable of inducing various phase II enzyme systems. However, the observed increase in oxidative DNA damage raises the question of whether greatly increased ingestion of cruciferous vegetables is beneficial.
Originalsprog | Engelsk |
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Tidsskrift | Food and Chemical Toxicology |
Vol/bind | 39 |
Udgave nummer | 6 |
Sider (fra-til) | 533-40 |
Antal sider | 8 |
ISSN | 0278-6915 |
Status | Udgivet - jun. 2001 |
Nolte, H., Backer, V. & Porsbjerg, C., dec. 2001, I: Annals of Allergy, Asthma, & Immunology. 87, 6 Suppl 3, s. 7-11 5 s.
Publikation: Bidrag til tidsskrift › Review › peer review
Træden, U. I., Zwisler, A-DO., Møller, L. & Tønnesen, H., 2001, København: Clinical Unit of Health Promotion.
Publikation: Bog/antologi/afhandling/rapport › Bog › Forskning
Originalsprog | Dansk |
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Udgivelsessted | København |
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Forlag | Clinical Unit of Health Promotion |
Status | Udgivet - 2001 |
Kjaer, S. K., Chackerian, B., van den Brule, A. J., Svare, E. I., Paull, G., Walbomers, J. M., Schiller, J. T., Bock, J. E., Sherman, M. E., Lowy, D. R. & Meijer, C. L., feb. 2001, I: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10, 2, s. 101-6 6 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Petersen, J. S., Andersen, D., Muntzel, M. S., Diemer, N. H. & Holstein-Rathlou, N. H., nov. 2001, I: American Journal of Hypertension. 14, 11 Pt 1, s. 1116-22 7 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Parving, H. H., Hommel, E., Jensen, B. R. & Hansen, H. P., jul. 2001, I: Kidney International. 60, 1, s. 228-34 7 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Pedersen, P. M., Jørgensen, H. S., Kammersgaard, L. P., Nakayama, H., Raaschou, H. O. & Olsen, T. S., sep. 2001, I: American Journal of Physical Medicine and Rehabilitation. 80, 9, s. 685-92 8 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Originalsprog | Engelsk |
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Tidsskrift | American Journal of Physical Medicine and Rehabilitation |
Vol/bind | 80 |
Udgave nummer | 9 |
Sider (fra-til) | 685-92 |
Antal sider | 8 |
ISSN | 0894-9115 |
Status | Udgivet - sep. 2001 |
Boesen, M. P., Falck Larsen, C., Lippert, F. K., Schultz Larsen, M., Röck, N. D. & Lang-Jensen, T., 2001, 3 s.
Publikation: Andet › Andet bidrag › Forskning
Originalsprog | Dansk |
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Publikationsdato | 2001 |
Antal sider | 3 |
Status | Udgivet - 2001 |
Van Lieshout, J. J., Pott, F., Madsen, P. L., Van Goudoever, J. & Secher, N. H., 2001, I: Stroke. 32, 7, s. 1546-1551 6 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Lei, U., Masmas, T. N. & Frentz, G., 2001, I: Acta Dermato-Venereologica. 81, 6, s. 415-7 3 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Spies, C., Tønnesen, H., Andreasson, S. & Helander, A., 2001, I: Alcoholism: Clinical and Experimental Research. 25
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Originalsprog | Engelsk |
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Tidsskrift | Alcoholism: Clinical and Experimental Research |
Vol/bind | 25 |
ISSN | 0145-6008 |
Status | Udgivet - 2001 |
Christensen, O. M., Christiansen, T. C., Krasheninnikoff, M., Lind, B., Hölmich, L. R., Hansen, F. F., Rathje, G. S. & Hölmich, P. 2001 I : International Orthopaedics. 24, 6, s. 358-60 3 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
We compared two different treatments for displaced distal radius Colles' type fractures (Older type 3 and 4), at two hospitals. We found bridging external fixation superior to reduction and fixation in a dorsal plaster cast regarding both the end-anatomic results at 3 months and the functional scores at 3 and 9 months (modified Gartland and Werley).
Originalsprog | Engelsk |
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Tidsskrift | International Orthopaedics |
Vol/bind | 24 |
Tidsskriftsnummer | 6 |
Sider (fra-til) | 358-60 |
Antal sider | 3 |
ISSN | 0341-2695 |
Status | Udgivet - 2001 |
Morré, S. A., van Dijk, R., Meijer, C. J., van den Brule, A. J., Kjaer, S. K. & Munk, C., jun. 2001, I: Journal of Clinical Microbiology. 39, 6, s. 2375-6 2 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review