Published in 2007

Diverging mechanisms for TNF-alpha receptors in normal mouse brains and in functional recovery after injury: From gene to behavior

Quintana, A., Molinero, A., Florit, S., Manso, Y., Comes, G., Carrasco, J., Giralt, M., Borup, R., Nielsen, F. C., Campbell, I. L., Penkowa, M. & Hidalgo, J., sep. 2007, I: Journal of Neuroscience Research. 85, 12, s. 2668-85 18 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Impairment of the dynamic control of the lumbopelvic complex in LBP has gained increased focus both clinically and experimentally. The objectives of this study were to determine the reliability of inclinometry as a measure of dynamic lumbopelvic control. Lumbopelvic reposition accuracy during pelvic tilts was measured in 39 healthy subjects using an inclinometer attached to the skin at S2 level. The reposition accuracy was measured in sitting, standing and supported standing. Tests were performed three times with a 20 min recess between tests. Only data from the last two test sequences were used in order to account for learning effects. Intraclass correlation coefficients were low for the sitting (0.54) and supported standing positions (0.36). In the standing position, a significant difference between test and retest was observed (P = 0.003) and further reliability analysis was therefore abandoned. It is concluded that inclinometry is not reliable for measuring the dynamic lumbopelvic control in any of the test positions and prior work utilising inclinometry to evaluate dynamic lumbopelvic control should be interpreted with caution.

Originalsprog Engelsk
Tidsskrift European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Vol/bind 16
Udgave nummer 6
Sider (fra-til) 733-40
Antal sider 8
ISSN 0940-6719
DOI
Status Udgivet - jun. 2007

Effect of 1,25-dihydroxy-vitamin D3 in experimental sepsis

Møller, S., Laigaard, F., Olgaard, K. & Hemmingsen, C., 10 jul. 2007, I: International Journal of Medical Sciences. 4, 4, s. 190-5 6 s.

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Endoleaks after endovascular aneurysm repair lead to nonuniform intra-aneurysm sac pressure

Dias, N. V., Ivancev, K., Resch, T. A., Malina, M. & Sonesson, B., aug. 2007, I: Journal of Vascular Surgery. 46, 2, s. 197-203 7 s.

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Enhanced satellite cell proliferation with resistance training in elderly men and women

Mackey, A. L., Esmarck, B., Kadi, F., Koskinen, S. O. A., Kongsgaard, M., Sylvestersen, A., Hansen, J. J., Larsen, G. & Kjaer, M., feb. 2007, I: Scandinavian journal of medicine & science in sports. 17, 1, s. 34-42 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Epidemiological and clinical studies on hand eczema in a population-based twin sample

Jørkov, A. L., 2007, Københavns Universitet.

Publikation: Bog/antologi/afhandling/rapportPh.d.-afhandling

Experimental quadriceps muscle pain impairs knee joint control during walking

Henriksen, M., Alkjaer, T., Lund, H., Simonsen, E. B., Graven-Nielsen, T., Danneskiold-Samsøe, B. & Bliddal, H., jul. 2007, I: Journal of applied physiology (Bethesda, Md. : 1985). 103, 1, s. 132-9 8 s.

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Pain is a cardinal symptom in musculoskeletal diseases involving the knee joint, and aberrant movement patterns and motor control strategies are often present in these patients. However, the underlying neuromuscular mechanisms linking pain to movement and motor control are unclear. To investigate the functional significance of muscle pain on knee joint control during walking, three-dimensional gait analyses were performed before, during, and after experimentally induced muscle pain by means of intramuscular injections of hypertonic saline (5.8%) into vastus medialis (VM) muscle of 20 healthy subjects. Isotonic saline (0.9%) was used as control. Surface electromyography (EMG) recordings of VM, vastus lateralis (VL), biceps femoris, and semitendinosus muscles were synchronized with the gait analyses. During experimental muscle pain, the loading response phase peak knee extensor moments were attenuated, and EMG activity in the VM and VL muscles was reduced. Compressive forces, adduction moments, knee joint kinematics, and hamstring EMG activity were unaffected by pain. Interestingly, the observed changes persisted when the pain had vanished. The results demonstrate that muscle pain modulated the function of the quadriceps muscle, resulting in impaired knee joint control and joint instability during walking. The changes are similar to those observed in patients with knee pain. The loss of joint control during and after pain may leave the knee joint prone to injury and potentially participate in the chronicity of musculoskeletal problems, and it may have clinically important implications for rehabilitation and training of patients with knee pain of musculoskeletal origin.

Originalsprog Engelsk
Tidsskrift Journal of applied physiology (Bethesda, Md. : 1985)
Vol/bind 103
Udgave nummer 1
Sider (fra-til) 132-9
Antal sider 8
ISSN 8750-7587
DOI
Status Udgivet - jul. 2007

Five-hour diagnosis of dermatophyte nail infections with specific detection of Trichophyton rubrum

Brillowska-Dabrowska, A., Saunte, D. M. & Arendrup, M. C., apr. 2007, I: Journal of Clinical Microbiology. 45, 4, s. 1200-4 5 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Forbruget af antiastmatisk medicin blandt danske sportsfolk

Lund, T. K., Pedersen, L. & Backer, V., 10 dec. 2007, I: Ugeskrift for Laeger. 169, 50, s. 4355-9 5 s.

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Guillain-Barré syndrome associated to infection with Borrelia burgdorferi: A case report

von Linstow, M. L. & Andersen, J., 2007, I: Journal of Pediatric Infectious Diseases. 2, 4, s. 247-250 4 s.

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In vivo efficacy and pharmacokinetics of voriconazole in an animal model of dermatophytosis

Saunte, D. M., Simmel, F., Frimodt-Moller, N., Stolle, L. B., Svejgaard, E. L., Haedersdal, M., Kloft, C. & Arendrup, M. C., sep. 2007, I: Antimicrobial Agents and Chemotherapy. 51, 9, s. 3317-21 5 s.

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Increased cancer risk in patients referred to hospital with suspected fibromyalgia

Dreyer, L., Mellemkjaer, L., Kendall, S., Jensen, B., Danneskiold-Samsøe, B. & Bliddal, H., jan. 2007, I: Journal of Rheumatology. 34, 1, s. 201-6 6 s.

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OBJECTIVE: To analyze whether fibromyalgia (FM) and FM-like symptoms are related to an increased incidence of cancer.

METHODS: We identified 1361 patients referred on suspicion of FM in the period 1984-99 from hospital records. Following the American College of Rheumatology (ACR) criteria, patients were divided into subgroups with and without confirmed FM. The cohort was followed to the end of 1999 and linked to the files of the Danish Cancer Register. Site-specific standardized incidence ratios (SIR) were calculated.

RESULTS: We found no association between FM and cancer in 1132 female patients with confirmed FM at our institution (SIR 1.2, 95% CI 0.8-1.8). In 106 women referred for muscle pain and/or tenderness who did not meet the criteria for FM, an increased overall SIR was observed (SIR 2.5, 95% CI 1.2-4.6), with increased risk for breast cancer (SIR 4.8, 95% CI 1.6-11.3) and lymphatic and hematological cancers (SIR 10.6, 95% CI 1.2-38.2). There were 4 lung cancers in 84 men with confirmed FM (SIR 12.6, 95% CI 3.4-32.4).

CONCLUSION: Neither confirmed FM nor those without confirmed FM predicted cancer. An increased risk of breast cancer was found among those who did not meet the ACR criteria for FM. These patients should be investigated if they develop any new or warning symptoms of malignancy, and treating physicians should be vigilant with screening procedures such as mammography.

Originalsprog Engelsk
Tidsskrift Journal of Rheumatology
Vol/bind 34
Udgave nummer 1
Sider (fra-til) 201-6
Antal sider 6
ISSN 0315-162X
Status Udgivet - jan. 2007

Inhibition of the renin-angiotensin system abolishes the proatherogenic effect of uremia in apolipoprotein E-deficient mice

Bro, S., Binder, C. J., Witztum, J. L., Olgaard, K. & Nielsen, L. B., maj 2007, I: Arteriosclerosis, Thrombosis, and Vascular Biology. 27, 5, s. 1080-6 7 s.

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Intra-observer and inter-observer agreement of the manual examination of the lumbar spine in chronic lowback pain

Qvistgaard, E., Rasmussen, J. H., Laetgaard, J., Hecksher-Sørensen, S. & Bliddal, H., feb. 2007, I: European Spine Journal. s. 277-82

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Intratumor genetic heterogeneity of breast carcinomas as determined by fine needle aspiration and TaqMan low density array

Lyng, M. B., Laenkholm, A-V., Pallisgaard, N., Vach, W., Knoop, A., Bak, M. & Ditzel, H. J., 2007, I: Cellular oncology : the official journal of the International Society for Cellular Oncology. 29, 5, s. 361-72 12 s.

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Introduction of new guidelines for emergency patients: motivational counselling among smokers

Backer, V., Nelbom, B. M., Duus, B. R. & Tønnesen, H., 1 jul. 2007, I: Clinical Respiratory Journal. 1, 1, s. 37-41 5 s.

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Smoking is the most important risk factor for morbidity and mortality in hospital patients. Patient contact with the healthcare system should include smoking cessation counselling. Emergency admissions are seldom given this opportunity. Objective: The aim of the study was to illustrate the implementation of motivational counselling in a department of acute surgery.
Originalsprog Engelsk
Tidsskrift Clinical Respiratory Journal
Vol/bind 1
Udgave nummer 1
Sider (fra-til) 37-41
Antal sider 5
ISSN 1752-6981
DOI
Status Udgivet - 1 jul. 2007

Kissing stents in the common femoral artery bifurcation for critical limb ischemia: technical description and report of three cases

Mathisen, S. R., Akesson, M., Lindh, M., Ivancev, K. & Resch, T. A., 2007, I: Vascular. 15, 4, s. 211-4 4 s.

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Kønsforskelle ved autoimmune sygdomme illustreret ved reumatoid artritis

Danneskiold-Samsøe, B., Bartels, E. M. & Dreyer, L., 18 jun. 2007, I: Ugeskrift for læger [online]. 169, 25, s. 2440-2 3 s.

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Many autoimmune diseases like rheumatoid arthritis (RA) show gender differences. RA is triggered by an interaction between genetic, hormonal, environmental and behavioural factors. 75% of cases are women under the age of 60; lover the age 60 the gender ratio is 1:1. Different genotypes predispose for RA. Pregnancy often suppresses RA, as does oral contraception. Lactation, smoking (w), BMI > 30, heavy vibrations and certain dust particles (m) may trigger RA, while the effect of male hormones is uncertain. Future prevention should focus on environment, behavioural factors and genetic profiling.

Bidragets oversatte titel Gender differences in autoimmune diseases illustrated by rheumatoid arthritis
Originalsprog Dansk
Tidsskrift Ugeskrift for læger [online]
Vol/bind 169
Udgave nummer 25
Sider (fra-til) 2440-2
Antal sider 3
ISSN 1603-6824
Status Udgivet - 18 jun. 2007

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